Alterations in laryngopharyngeal reflux shortly after uvulopalatopharyngoplasty having obstructive snore: A keen observational data

Alterations in laryngopharyngeal reflux shortly after uvulopalatopharyngoplasty having obstructive snore: A keen observational data

Shisheng Li, Company out-of Otolaryngology Head and you may Neck Functions, Another Xiangya Health, Main Southern University, Changsha, Hunan 410000, China.

Shisheng Li, Company off Otolaryngology Direct and you will Shoulder Surgery, The next Xiangya Hospital, Central South College, Changsha, Hunan 410000, Asia.


To help you imagine laryngopharyngeal reflux (LPR) change immediately following uvulopalatopharyngoplasty (UPPP) getting obstructive sleep apnea (OSA) using the reflux symptom directory (RSI) and you can reflux seeking get (RFS) surveys.


A maximum of 91 professionals had been recruited and you will divided in to about three groups: manage (n = 27), OSA light to help you reasonable (letter = 29), and you may OSA significant (letter = 35) groups centered on polysomnography. Every professionals done new preoperative RSI, and you will underwent blinded evaluation on videolaryngoscopy using the RFS questionnaire. Thirty-four OSA people just who undergone UPPP businesses finished postoperative polysomnography and you may questionnaires once more shortly after an effective 6-few days follow-right up.


The RSI score and RFS were higher in patients with OSA than in those without OSA. Patients with severe OSA also had a higher RSI score and RFS than those with mild to moderate OSA. Apnea and hypopnea index degree and percentage of recording time for <90% oxygen saturation showed positive correlation with LPR symptoms. But the lowest blood oxygen saturation during the recording time was negatively correlated with LPR symptoms. The mean RSI score and RFS before UPPP surgery were ± 4.85 and ± 4.80, after surgery decreasing to 9.53 ± 4.16 and 8.65 ± 4.87, respectively (P <.05). In 25 patients where surgery was successful, RSI scores, RFSs and individual RSI variables decreased after surgery.


LPR symptoms are among OSA patients, in addition to coexistence regarding OSA and LPR can’t be neglected. Effective UPPP operations possibly decreases LPR episodes and advances laryngoscopic signs by alleviating sleep breathing issues.

step 1 Introduction

Obstructive anti snoring (OSA) try a growing health matter. Everything dos%–4% away from middle-old individuals experience OSA. step one OSA is described as repeated failure and you will reopening of your own upper airway while sleeping resulting in intermittent hypoxia and you may sleep fragmentation. 2 Periodic hypoxia was a condition when apnea/hypopnea occurs, and fresh air have into blood are less. Periodic hypoxia causes general pain and you will oxidative be concerned and you will mation. step 3 To alleviate which periods, continued positive airway stress (CPAP) otherwise operations are treatments applied to OSA.

CPAP decreases reflux occurrences and you will improves clinical symptoms of gastroesophageal reflux problem (GERD) and you can laryngopharyngeal reflux (LPR) in people having OSA, like heartburn grievances. 4-six Just like the a great and you may noninvasive answer to OSA, CPAP retains a particular confident stress on the higher airway so you can boost higher airway collapse. Research has shown you to definitely CPAP decreases both GERD and you can LPR attacks from the increasing esophageal internal pressure, 4, eight and you may response contraction of straight down esophageal anal sphincter (LES), 8 limiting reflux period and you may reducing esophageal acidification. OSA and LPR are two problems that produce persistent upper airway inflammation. Within the OSA people, coexistence which have LPR is very repeated, are found in 20%–67% out of people. nine, ten Whilst the association between OSA and LPR has been has just investigated, they nonetheless remains questionable. While some studies have displayed you to definitely CPAP procedures somewhat aisle-datingwebsite advances reflux periods from inside the OSA customers, eleven simply couple has examined the effect regarding cosmetic plastic surgery to have OSA on reflux state.

Uvulopalatopharyngoplasty (UPPP) try a widely recognized functions getting OSA several and you may very first suggested from the Fujita mais aussi al. 13 This has been recently enhanced fourteen towards goal of reducing the oropharyngeal congestion by detatching redundant mucosal retracts, hypertrophic tonsils, and you will a very thickened and you may elongated softer palate. fifteen UPPP can get relieve the severity out of OSA during the clients whose congestion website has reached the palatopharyngeal top.

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